Examination of sex differences in fatty acid ethyl ester and ethyl glucuronide hair analysis

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Workplace alcohol testing program by combined use of ethyl glucuronide and fatty acid ethyl esters in hair.

AIMS The applicability of fatty acid ethyl esters (FAEEs) and ethyl glucuronide (EtG) in hair in a workplace alcohol testing program was investigated. METHODS A total of 78 hair samples from employees in jobs with a high endangering potential were tested for EtG and FAEEs. In most cases excessive drinking was suspected. For 59 of these cases additional data of the traditional alcohol markers ...

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Influence of hair straightening on ethyl glucuronide content in hair

Aims: The aim of the study was to analyse ETG in hair samples treated by a hair straightener. Methods: Positive EtG hair samples were treated with hair straightener during 1 min at 200°C. Treated and non treated hair were analysed for EtG by GC/MS-NICI after solid phase extraction and heptafluorobutyric anhydride derivatization . Results: In 11 samples an average decrease was found 24% and in 5...

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Clinical sensitivity and specificity of meconium fatty acid ethyl ester, ethyl glucuronide, and ethyl sulfate for detecting maternal drinking during pregnancy.

BACKGROUND We investigated agreement between self-reported prenatal alcohol exposure (PAE) and objective meconium alcohol markers to determine the optimal meconium marker and threshold for identifying PAE. METHODS Meconium fatty acid ethyl esters (FAEE), ethyl glucuronide (EtG), and ethyl sulfate (EtS) were quantified by LC-MS/MS in 0.1 g meconium from infants of Safe Passage Study participan...

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Agreement between the fatty acid ethyl ester hair test for alcohol and social workers' reports.

The purpose of this study was to examine the relationship between social worker reports and the fatty acid ethyl ester (FAEE) test as a biomarker for heavy alcohol use. In 2005, a diagnostic program to detect excessive alcohol use by FAEE hair analysis in parents at high risk of having children with fetal alcohol spectrum disorders was established. All cases submitted by Child Protective Servic...

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Method to assess fatty acid ethyl ester binding to albumin.

AIMS To develop a method to assess the relative binding of fatty acid ethyl esters (FAEE) and free fatty acids (FFA) to albumin, and to determine if binding affinity is related to fatty acid chain length and or degree of saturation. METHODS Radiolabelled ethyl-[14C] oleate bound to albumin was challenged with various ratios of FFA to FAEE. The displacement of ethyl-[14C] oleate by FFA was vis...

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ژورنال

عنوان ژورنال: Drug Testing and Analysis

سال: 2014

ISSN: 1942-7603

DOI: 10.1002/dta.1653